noun (n)

• (medicine) a malignant state; progressive and resistant to treatment and tending to cause death(noun.state)

  Synonym:
  malignance
  

  source: wordnet30
• quality of being disposed to evil; intense ill will(noun.attribute)

  Synonym:
  malignance, malignity
  Antonym:
  benignancy, benignity, graciousness
  

  source: wordnet30